HIGHLIGHTS †
Japan’s Education Ministry (MEXT) launches interdisciplinary research hub program to foster collaborative innovation across institutions from October 2025 (MEXT web)
Project title: Interdisciplinary Frontier Hub for Enhancing Planetary Resilience through Low-Temperature Plasma Science and Genetics
Human survival is increasingly threatened by the limits of the planetary boundaries. To address these challenges and enhance the sustainability of agriculture, forestry, and fisheries, this project aims to strengthen planetary resilience by leveraging low-temperature plasma technologies to regulate epigenetics—without relying on fossil fuels. Instead, it utilizes atmospheric resources, water, and renewable energy.
The initiative will establish a cross-disciplinary research network that integrates plasma science and genetics, creating a new academic domain that bridges these fields. This hub will contribute to food security and global sustainability by pioneering innovative approaches to biological control and environmental adaptation.
Terminology– What is Epigenetics?: 🧬 Epigenetics refers to the study of changes in gene expression that do not involve alterations to the underlying DNA sequence. These changes can be triggered by environmental factors, chemical signals, or physical stimuli, and they influence how genes are turned on or off. In agriculture and life sciences, epigenetic regulation is a promising tool for enhancing stress resistance, improving crop traits, and adapting organisms to changing environments—all without genetic modification.
事業名:地球レジリエンス強化に向けた低温プラズマ学と遺伝学のフロンティア学際ハブ
概要: 人類の生存は、プラネタリーバウンダリー(地球の限界)によれば、ますます脅かされています。これらの課題に対応し、農林水産業の持続可能性を高めるため、本事業では化石燃料に依存せず、大気・水・再生可能エネルギーを活用し、低温プラズマ技術によるエピジェネティクス制御を通じて、地球レジリエンスの強化を目指します。
この取り組みでは、低温プラズマ学と遺伝学を融合させた新たな学術領域の創成を目指し、異分野融合型の研究ネットワークを構築します。食料安全保障や国際的課題への対応に貢献する革新的な生物制御技術や環境適応技術の開発を推進します。
実施期間: 2025年度より2034年度
用語解説: 🔬 エピジェネティクス(Epigenetics) とは、DNAの塩基配列そのものを変えることなく、遺伝子の働き方(発現)を制御する仕組みを指します。環境要因や化学的刺激によって、遺伝子のオン・オフが調整されることで、生物の性質や反応が変化します。農業や医療分野では、エピジェネティクスを活用することで、作物の耐性強化や病気の予防などに応用が期待されています。
Review has been published.
Plasma-assisted material processing (Go to publication (link)). Plasma process hierarchy comprises heterogeneous phases of plasma, sheath, and surface (Link to Fig), Mechanisms behind the cyclic atomic layer etching processes (Link to Fig.)
Grant-in-Aid for Transformative Research Areas (A) has been started from April, 2024
Project area name is "Plasma-driven seed memory operation: Frontiers in molecular dynamics in seeds driven by plasma"
24H02254 "プラズマ駆動生化学反応の学理構築:活性種の動態解析" (KAKEN) Principal investigator: Kenji Ishikawa
Plasma-based in situ functionalization based on functional nitrogen science
Functional nitrogen science is now emerged for effective utilization of reactive nitrogen species (RNS). The technologies are related to water and air plasma-based nitrogen fixation. Electron impact reactions and chemical reactions among nitrogen, oxygen, and hydrogen, can occur on non-equilibrium plasma processing. Key issues are on in situ generation of RNS at the point of use and plasma-based nitrogen cycles of ammonia and nitric acid. (link to) Ishikawa Jpn. J. Appl. Phys. 61 SA0802 (2022).
Nitrogen derivatives (Diagram): Short-lived nitrogen derivatives react to generate various RNS in situ through oxidation and hydrogenation.
Upcoming meeting †
Color: Oversea, Domestic
2026
- January 28, 2026
- 教務委員会
- January 29, 2026
- 相談会
- February 2, 2026
- 講義(16)誘電体工学 (試験)
- February 3, 2026
- 講義(16)電磁気学Ⅰ (試験)
- February 5, 2026
- 公聴会 Du,小野浩毅 於:FUJIホール
- February 7, 2026
- 受賞記念講演 馬場嘉信
- February 12-13, 2026
- 修士論文発表会
- February 14, 2026
- サタデーモーニングプラズマ講座
- February 17, 2026
- 東京大学
- February 18, 2026
- 公聴会 孫こう達,吉江泰斗
- February 19, 2026
- 文科省来学
- February 19, 2026
- 卒研発表会
- February 20, 2026
- プラズマグリーン・DXコンソーシアム 研究会
- February 20-21, 2026
- プラズマ種子科学研究会,学変(a) 全体会議 於:山形蔵王
- February 23-24, 2026
- 日韓アドミックプロセスワークショップ 於:熊本KOKOホテル
- February 25-26, 2026
- 会議
- February 25, 2026
- 公聴会 Kim
- February 26, 2026
- Global plasma forum
- February 27, 2026
- 相談会,教務委員会
- March 1, 2026
- 台湾ワークショップ
- March 2-7, 2026
- ISPlasma ISPlasma 2026, Japan. to be held at Meijo University. Dr Ishikawa will have an invited talk entitled "Pioneer of Plasma Interactions with Biological and Organic Liquids: In Memory of Professor William “Bill” Graham (1949–2025)". (web)
- March 3, 2026
- 第二回ワークショップ(台湾・国立清華大学)
- March 7, 2026
- 最終講義 梅原徳次
- March 7, 2026
- 最終講義 豊田浩孝
- March 10, 2026
- Global plasma forum lecture of prof. Tiberiu Minea
- March 12, 2026
- 相談会
- March 13, 2026
- 最終講義 豊國伸哉
- March 14, 2026
- 最終講義 武田一哉
- March 14, 2026
- 令和8年電気学会全国大会 於:東北学院大学 (Web) シンポジウム「御された雷ープラズマーによる植物の発芽・成長制御の科学」 to be held at 13:00 to 17:00
- March 15-18, 2026
- 応物春 2026年(令和8年)第73回応用物理学会 春季学術講演会 to be held at University of Tokyo Science, Okayama, Tokyo, Japan. Mar 17, 13:30 シンポジウム:プラズマが誘起する植物応答, March 15, 9:00 シンポジウム:原子層プロセス(ALP:Atomic Layer Process)の解析技術と応用技術(3),
- March 17, 2026
- 第1回委員会~
- March 18, 2026
- 教務委員会
- March 19-21, 2026
- アイントフォーヘン工科大学訪問
- March 23, 2026
- 学際ハブ公開シンポジウム
- March 25, 2026
- 卒業式
- March 27, 2026
- 総括班会議 10:00 於:九州大学 伊都キャンパス
- March 27, 2026
- 最終講義 白谷正治
- March 28-29, 2026
- 第261回日本作物学会 於:高崎健康福祉大学 群馬 (Web) シンポジウム「プラズマ種子科学」
- March 30, 2026
- 会合
- March 31, 2026
- 第1回委員会
- April 21, 2026
- (Closed) R052 DXプラズマ研究会 2026年度第1回研究会 於:東京
- April 24, 2026
- ~第1回委員会
- April 27-May 1, 2026
- 2026 MRS Spring Meeting and JSAP-MRS Joint Symposia 2026 to be held at Hawaii Convention Center, Honolulu, Hawaii, USA
- April 28, 2026
- 第2回委員会
- May 15, 2026
- ~第2回委員会
- May 19, 2026
- 第3回委員会
- May 29, 2026
- ~第3回委員会
- May 31-June 5, 2026
- ICPM International Conference on Plasma Medicine (ICPM) to be held at Gifu, Japan. (web)
- June 8, 2026
- 電気物理数学 講義担当
- June 15, 2026
- 電気物理数学 講義担当
- June 17, 2026
- (Closed) R052 DXプラズマ研究会 2026年度第2回研究会 於:東京
- June 22-26, 2026
- ICOPS to be held at Statelone, Lake Tahoe NV, USA (Web)
- July 7-11, 2026
- (not attend) XXVII ESCAMPIG (Europhysics Conference on Atomic and Molecular Physics of Ionized Gases) to be held at Madeira, Portugal.
- August 18-21, 2026
- 打ち合わせ
- August 25-28, 2026
- (not attend) Summer School and International Symposium on the Physics of Ionized Gases (SPIG 2026) to be held at Belgrade, Serbia. (Web)
- August 31-September 3, 2026
- (not attend) 20th International Conference on Plasma Surface Engineering (PSE 2026), to be hld at Erfurt, Germany
- September 3, 2026
- (Closed) R052 DXプラズマ研究会 2026年度第3回研究会 於:東京
- September 8-11, 2026
- 応物秋 2026年(令和8年)応用物理学会 秋季学術講演会 to be held at Hokkaido University, Japan.
- September 21-26, 2026
- AAPPS-DPP AAPPS-DPP2024 Annual Conference to be held at Exhibition and Convention Center in Busan port (BPEX), Korea
- October 24, 2026
- 熱帯シンポジウム 於:名古屋大学
- November 2-6, 2026
- GEC 79th Gaseous Electronics Conference (GEC 26) to be held at Chicago, USA. Dr Ishikawa will have an invited talk of "Leading-edge semiconductor plasma-processing via energy-efficient, environmentally benign, and evolutionary techniques"
- November 8-13, 2026
- AVS AVS 73rd International Symposium & Exhibition, to be held at Pittsburgh, Pennsylvania, USA. Dr Ishikawa will chair the plasma science and technology division.
- November 19-20, 2026
- DPS 47th DPS to be held at Tokyo, Japan.
- November 24, 2026
- (Closed) R052 DXプラズマ研究会 2026年度第4回研究会 於:東京
- November 30 - December 2, 2026
- ICRP ICRP-12 to be held at Kanazawa, Japan. (Web)
- December , 2026
- プラズマ核融合学会
2027
- January 19-20, 2027
- (Closed) R052 DXプラズマ研究会 2026年度第5回研究会 於:東京
- March 2-6, 2027
- ISPlasma ISPlasma 2027, to be held at Nagoya University, Japan.
- June , 2027
- IWOPA6 6th International Workshop on Plasma Agriculture (IWOPA) to be held at Ishigakijima, Okinawa, Japan.
- October , 2027
- GEC 80th Gaseous Electric Conference (GEC) to be held at Lisbone, Portugal.
- November , 2027
- AVS AVS 74th International Symposium & Exhibition, to be held at USA.
- November , 2027
- 48th DPS to be held at Kyshu, Japan.
2028
- September , 2028
- GEC 81st Gaseous Electric Conference (GEC) to be held at Montreal, Canada.
- November , 2028
- AVS AVS 75th International Symposium & Exhibition, to be held at USA.
meeting2026, meeting2025, meeting2024, meeting2023, meeting2022, meeting2021, meeting2020, meeting2019, meeting2018, meeting2017, meeting2016, meeting2015, meeting2014, meeting2013, meeting2012, meeting2011
JSPF calendar, MRS calendar, APS calendar, conferences calendar
HIGHLIGHTS (II)
Metabolomic profiles display a novel mechanism on cell death that is induced specifically by incubation in the non-thermal plasma treated solutions
The plasma-activated lactated solution (PAL) exhibits antitumor effects in glioblastoma U251SP cells. The PAL-treated U251SP cells exhibited changes in intracellular metabolites that were reductive in the redox state.
Non-thermal plasma–activated lactate solution kills U251SP glioblastoma cells in an innate reductive manner with altered metabolism
Kenji Ishikawa, Yugo Hosoi et al. Archives of Biochemistry and Biophysics 688, 108414 (pp. 1-9) (July 30, 2020). link
Nonthermal plasma-activated medium (PAM) modified metabolomic profiles in glycolysis of U251SP glioblastoma
Naoyoyuki Kurake, Kenji Ishikawa et al. Archives of Biochemistry and Biophysics 662, pp.83-92 (February 15, 2019). link
Real-time in situ ESR
Our paper was published on-line in the Applied Physics Letters (IF 2011 = 3.844) on July 2 issue of 2012.
Real-time In Situ Electron Spin Resonance Measurements on Fungal Spores of Penicillium digitatum during Exposure of Oxygen Plasmas
Kenji Ishikawa et al. Appl. Phys. Lett. 101, 013704 (2012). link, arXiv
Real-time in situ ESR
Our paper was published in the Journal of Physical Chemistry Letters (I.F. 2011 = 6.213)
link
Synergistic Formation of Radicals by Irradiation with both Vacuum Ultraviolet and Atomic Hydrogen: a Real-time in situ Electron Spin Resonance Study
We report on the surface modification of polytetrafluoroethylene (PTFE) as an example of soft- and bio-materials that occur under plasma discharge by kinetics analysis of radical formation using in situ real-time electron spin resonance (ESR) measurements. During irradiation with hydrogen plasma, simultaneous measurements of the gas-phase ESR signals of atomic hydrogen and the carbon dangling bond (C-DB) on PTFE were performed. Dynamic changes of the C-DB density were observed in real time, where the rate of density change was accelerated during initial irradiation and then became constant over time. It is noteworthy that C-DBs were formed synergistically by irradiation with both vacuum ultraviolet (VUV) and atomic hydrogen. The in situ real-time ESR technique is useful to elucidate synergistic roles during plasma surface modification.
Kenji Ishikawa et al. J. Phys. Chem. Lett. 2, 1278 (2011). link
This paper won the 11th Plasma Electronics Award awarded by the Plasma Electronics division of the Japanese Society of Applied Physics on March 28, 2013.
Copyright Kenji Ishikawa (c) 2009-2025 Center for Low-temperature plasma sciences, Nagoya University.