Plasma-based in situ functionalization based on functional nitrogen science

Functional nitrogen science is now emerged for effective utilization of reactive nitrogen species (RNS). The technologies are related to water and air plasma-based nitrogen fixation. Electron impact reactions and chemical reactions among nitrogen, oxygen, and hydrogen, can occur on non-equilibrium plasma processing. Key issues are on in situ generation of RNS at the point of use and plasma-based nitrogen cycles of ammonia and nitric acid. (link to) Ishikawa Jpn. J. Appl. Phys. 61 SA0802 (2022).

Nitrogen derivatives (Diagram): Short-lived nitrogen derivatives react to generate various RNS in situ through oxidation and hydrogenation.

Upcoming meeting

Color: Oversea, Domestic


December 28-30, 2022
15th International Conference on Plasma Science and Applications (ICPSA2022) to be held online. (Web) Dr Ishikawa will have an invited talk of "Non-thermal plasma-activated lactated solution altered metabolisms in cancer cells" on December 30.


January 9-12, 2023
7th International Conference on Advances in Functional Materials (AFM) "Development of Functional Materials for a Better World" to be held at Centennial Hall, Kyushu University, Japan. (Web) Deadline: July 31, 2022
January 14-15, 2023
January 21, 2023
第16回サタデーモーニングプラズマプロセス講座 オンライン 勝又竜太・キオクシア モデレータ:石川健治
January 27, 2023
学振153委員会 第161回研究会『プラズマ千夜一夜物語:プラズマ材料科学分野の歴史と将来展望』 於:東京・京橋 (Closed) (Web) Dr Ishikawa will facilitate the panel session.
January 28, 2023
学振153委員会 拡大運営企画会議 於:東京 (Closed, in Japanese)
January 31, 2023
九州大学 伊都キャンパス (Closed, in Japanese)
February 9-10, 2023
修論発表会 於:名古屋大学 IB電子情報館 (Closed, in Japanese)
February 10, 2023
第5回 Atomic Layer Process (ALP) Workshop (in Japanese) 於:大阪大学豊中キャンパス 大学会館 (Web)
February 11, 2023
第17回サタデーモーニングプラズマプロセス講座 昌原 明植・産総研 オンライン モデレータ:堀 勝
February 13, 2023
夏目 公聴会 オンライン
February 16, 2023
劉,岩田 公聴会 オンライン
February 22, 2023
NIBB visit
February 23-24, 2023
プラズマ種子科学研究会 於:坂田平田ホール IB電子情報館 大講義室 (Web)
February 24, 2023
グリーン・DXプラズマコンソーシアム第5回講演会 於:坂田平田ホール
February 26-March 2, 2023
SPIE Advanced Etch Technology and Process Integration for Nanopatterning XII (AL106) to be held at San Jose USA. (Web) Dr Shinoda will have a presentation.
March 1, 2023
Report radiation research
March 5-9, 2023
ISPlasma 2023 to be held at Gifu, Japan. (web) Dr Ishikawa will have a Keynote presentation on March 9, 2023.
March 11, 2023
第18回サタデーモーニングプラズマプロセス講座 オンライン 灘原 モデレータ 堀 勝
March 13-17, 2023
International workshop on plasma cancer therapy (IWPCT) 2023 to be held in Raleigh, NC, USA.
March 15-18, 2023
応物春 2023年(令和5年)第70回応用物理学会春季学術講演会 於:上智大学 to be held on Sophia University, Tokyo, Japan. T19シンポジウム プラズマ駆動科学とは何か~新しいプラズマプロセスの展開を期待して T19 symposium "What is Plasma-Driven Science - Expectations for New Developments in Plasma Processes" will be held on March 16, 2023 and will be chaired by Dr Ishikawa.
March 26, 2023
Global Plasma Forum(GPF)& 堀勝教授最終講義 於:名古屋大学豊田講堂
April 8, 2023
第19回サタデーモーニングプラズマプロセス講座 オンライン 五十嵐 モデレータ 中塚 理
April 15, 2023
International conference on electronic packaging (ICEP2023) to be held at Civic Auditorium Sears Home Yume Hall, Kumamoto, Japan. (Web)
April 16-21, 2023
4th International Conference on Data Driven Plasma Science (ICDDPS-4) to be held at Okinawa Institute of Science and Technology (OIST), Okinawa, Japan. (Web)
May 21-26, 2023 May 15-20, 2022 May 23-28, 2021
ISPC 25th International Symposium on Plasma Chemistry (ISPC) to be held at Kyoto, Japan. (Web) Deadline: January 31, 2023
May 28-June 2, 2023
243rd ECS Meeting with the 18th International Symposium on Solid Oxide Fuel Cells (SOFC-XVIII) (Web)
June 20, 2023
July 9-14, 2023 Talk
ICPIG 35th International Conference on Phenomena in Ionized Gases (ICPIG)to be held at Egmond aan Zee, the Netherlands (Web) Dr Ishikawa will have an invited talk of "Plasma induced surface reactions: novel measurements and new insights". Deadline: March 3, 2023
September 10-14, 2023
20th International Symposium on Laser-Aided Plasma Diagnostics (LAPD20) to be held at Kyoto Garden Palace Hotel, Kyoto, Japan. (Web)
September 19-23, 2023
応物秋 2023年(令和5年)秋季学術講演会 to be held on Kumamoto Castle Hall, Kumamoto, Japan.
September 3-9, 2023
SSDM 55th International Conference on Solid State Devices and Materials (SSDM) to be held at Nagoya Congress Center, Japan. Short Course will be held on September 5, 2023.
September, 2023 February 7-11, 2022 September 26-30, 2021 Talk
AEPSE 13th Asian-European International Conference on Plasma Surface Engineering (AEPSE 2021) to be held at BEXCO, Busan, Korea. (Web) Dr Ishikawa will have a tutorial lecture of "Plasma in Healthcare : As tool of Regenerative Medicine and Development"
October, 2023
GEC 76th Gaseous Electric Conference (GEC) to be held at Ann Harbor, US. (web)
November 21-22, 2023
DPS Dry process symposium (DPS) to be held at Nagoya, Japan.
November 27-30, 2023
プラズマ核融合学会年会 於:岩手
December 11-16, 2023
(MRM2023) IUMRS-ICA Kyoto International Conference Center, Kyoto, Japan


March 15-18, 2023
応物春 2024年(令和6年)第71回応用物理学会春季学術講演会 to be held on Tokyo City University, Tokyo, Japan.

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Metabolomic profiles display a novel mechanism on cell death that is induced specifically by incubation in the non-thermal plasma treated solutions

The plasma-activated lactated solution (PAL) exhibits antitumor effects in glioblastoma U251SP cells. The PAL-treated U251SP cells exhibited changes in intracellular metabolites that were reductive in the redox state.

Non-thermal plasma–activated lactate solution kills U251SP glioblastoma cells in an innate reductive manner with altered metabolism

Kenji Ishikawa, Yugo Hosoi et al. Archives of Biochemistry and Biophysics 688, 108414 (pp. 1-9) (July 30, 2020). link

Nonthermal plasma-activated medium (PAM) modified metabolomic profiles in glycolysis of U251SP glioblastoma

Naoyoyuki Kurake, Kenji Ishikawa et al. Archives of Biochemistry and Biophysics 662, pp.83-92 (February 15, 2019). link

Real-time in situ ESR

Our paper was published on-line in the Applied Physics Letters (IF 2011 = 3.844) on July 2 issue of 2012.

Real-time In Situ Electron Spin Resonance Measurements on Fungal Spores of Penicillium digitatum during Exposure of Oxygen Plasmas

Kenji Ishikawa et al. Appl. Phys. Lett. 101, 013704 (2012). link, arXiv

Real-time in situ ESR

Our paper was published in the Journal of Physical Chemistry Letters (I.F. 2011 = 6.213)


Synergistic Formation of Radicals by Irradiation with both Vacuum Ultraviolet and Atomic Hydrogen: a Real-time in situ Electron Spin Resonance Study

We report on the surface modification of polytetrafluoroethylene (PTFE) as an example of soft- and bio-materials that occur under plasma discharge by kinetics analysis of radical formation using in situ real-time electron spin resonance (ESR) measurements. During irradiation with hydrogen plasma, simultaneous measurements of the gas-phase ESR signals of atomic hydrogen and the carbon dangling bond (C-DB) on PTFE were performed. Dynamic changes of the C-DB density were observed in real time, where the rate of density change was accelerated during initial irradiation and then became constant over time. It is noteworthy that C-DBs were formed synergistically by irradiation with both vacuum ultraviolet (VUV) and atomic hydrogen. The in situ real-time ESR technique is useful to elucidate synergistic roles during plasma surface modification.

Kenji Ishikawa et al. J. Phys. Chem. Lett. 2, 1278 (2011). link

This paper won the 11th Plasma Electronics Award awarded by the Plasma Electronics division of the Japanese Society of Applied Physics on March 28, 2013.

Copyright Kenji Ishikawa (c) 2009-2020 Center for Low-temperature plasma sciences, Nagoya University.

Last-modified: 2023-01-29 (日) 20:20:08